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Less common side effects of bicalutamide monotherapy in men include sexual dysfunction, depression, fatigue, weakness, and anemia. Bicalutamide is well tolerated and has few side effects in women. General side effects of bicalutamide that may occur in either sex include diarrhea, constipation, abdominal pain, nausea, dry skin, itching, and rash.
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
Common side effects of bicalutamide in men include breast growth, breast tenderness, and hot flashes. [10] Other side effects in men include feminization and sexual dysfunction. [22] [23] Some side effects like breast changes and feminization are minimal when combined with castration. [24]
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
Major side effects of bicalutamide [1] [2] [3] [4] [5] [6] [7]; Frequency Class of effect Effect Very common (≥10%) Reproductive system and breast disorders ...
Finasteride is increasingly being used by younger men even before they start to lose their hair. As finasteride use by younger men soars, some doctors caution about rare side effects Skip to main ...
[19] [20] [21] The median age of the patients was 73.5 years (range 59 to 91 years), and median duration of bicalutamide exposure was 7.5 weeks (range 1 to 312 weeks). [19] Cases of interstitial pneumonitis have also been reported in association with flutamide , nilutamide , and gonadotropin-releasing hormone (GnRH) agonists .
"The seasonal viral vaccines are very important in people over 50," Dr. Yancey says. "The flu shot, RSV vaccine and COVID booster can keep you out of the hospital and are lifesaving in some cases."