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Anhedonia is a diverse array of deficits in hedonic function, including reduced motivation or ability to experience pleasure. [1] While earlier definitions emphasized the inability to experience pleasure, anhedonia is currently used by researchers to refer to reduced motivation, reduced anticipatory pleasure (wanting), reduced consummatory pleasure (liking), and deficits in reinforcement learning.
Major depression was the leading cause of disease burden in North America and other high-income countries, and the fourth-leading cause worldwide as of 2006. In the year 2030, it is predicted to be the second-leading cause of disease burden worldwide after HIV , according to the WHO. [ 281 ]
It can be accompanied by depression, decreased motivation, or apathy. Lethargy can be a normal response to boredom, inadequate sleep, overexertion, overworking, stress, lack of exercise, or a symptom of a disorder. When part of a normal response, lethargy often resolves with rest, adequate sleep, decreased stress, and good nutrition. [23]
Depression affects around 14.8 million adults in the U.S. That?s around 7 percent of the entire population aged 18 and over.
Suddenly stopping a treatment or missing several doses may cause withdrawal-like symptoms. [7] Some studies have shown that antidepressants may increase short-term suicidal thoughts or actions, especially in children, adolescents, and young adults. However, antidepressants are more likely to reduce a person's risk of suicide in the long run. [7]
Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom, or a symptom of an underlying illness or disorder. It may also be a side effect of medication or caused by an interaction between medications or medication(s) and alcohol .
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