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Several anti-ulcer dosing regimens that combine antibiotics and proton pump inhibitors (PPI) to treat helicobacter pylori (H. pylori) induced peptic ulcer disease (PUD). The role of antibiotic in the therapies is to eradicate H. pylori, while the action of PPI is to reduce gastric acid secretion.
Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. [ 4 ] [ 5 ] An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer.
As a result, PUD that is associated with H. pylori is currently treated with antibiotics used to eradicate the infection. For decades prior to their discovery, it was widely believed that PUD was caused by excess acid in the stomach. During this time, acid control was the primary method of treatment for PUD, to only partial success.
Truncal vagotomy is a treatment option for chronic duodenal ulcers. [5] [6] It was once considered the gold standard, but is now usually reserved for patients who have failed the first-line "triple therapy" against Helicobacter pylori infection: two antibiotics (clarithromycin and amoxicillin or metronidazole) and a proton pump inhibitor (e.g., omeprazole).
Policy for population health "sets priorities" [2] and are a "guide to action to change what would otherwise occur". [2] Policies are based on "social sciences of sociology, economics, demography, public health, anthropology, and epidemiology" [4] and determine how outcomes can be accomplished are implemented at various levels. Such guides ...
PUD may refer to: Planned unit development; Public utility district; Peptic ulcer disease; Peeled undeveined shrimp; Polyurethane dispersion; Unitary Platform or Plataforma Unitaria Democrática, an opposition political party in Venezuela
A public health intervention is any effort or policy that attempts to improve mental and physical health on a population level. Public health interventions may be run by a variety of organizations, including governmental health departments and non-governmental organizations (NGOs). Common types of interventions include screening programs, [1 ...