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[6] [6] Peak concentrations of phentermine are reached 6 hours following oral administration of a dose of 15 mg. [6] The steady-state levels of phentermine with continuous administration have been found to be around 200 ng/mL in clinical studies. [6] The oral bioavailability of phentermine is not affected by intake of a high-fat meal. [6]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
In 1984, researchers at the University of Rochester Medical Center reported that they had performed a double-blind, controlled clinical trial comparing phentermine alone, fenfluramine alone, a combination of phentermine and fenfluramine, and placebo, for weight loss in humans. Weight loss in those receiving the fen-phen combination was ...
Chemically, it is a substituted phenethylamine and amphetamine and is closely related to phentermine and methamphetamine. [ 4 ] [ 9 ] [ 1 ] Mephentermine was first described and introduced for medical use by 1952. [ 10 ]
The combination of fenfluramine and phentermine was proposed in 1984. [8] Approximately 5 million people in the United States were given fenfluramine or dexfenfluramine with or without phentermine between 1996 and 1998.
In 2023, the state of New York passed a shield law that protects New York doctors who prescribe and send abortion pills to patients in states that have outlawed the procedure. It is one of several ...
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
Each pill contains 581.2 mg of nutgall tree, 19.2 mg of bitter apricot kernels, 19.2 mg of angular Solomon's seal, 12.8 mg of lotus seeds, 12.8 mg of squirrel's-foot fern, 12.8 mg of Chinese liquorice, 12.8 mg of Chinese cinnamon, 12.8 mg of fountainplant, and 6.4 mg of Mentha haplocalyx . [6] The Takabb Anti-Cough Pill is halal