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Sulfadimethoxine (or sulphadimethoxine, trade names Di-Methox or Albon) is a long-lasting sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections, including respiratory, urinary tract, enteric, and soft tissue infections [3] and can be given as a standalone or combined with ormetoprim to broaden the target range. [2]
Used together with pyrimethamine, a dihydrofolate reductase inhibitor, it is the treatment of choice for toxoplasmosis, which is caused by a protozoan parasite. [3] It is a second-line treatment for otitis media , prophylaxis of rheumatic fever , chancroid , chlamydia , and infections by Haemophilus influenzae . [ 1 ]
American soldiers were issued a first-aid kit containing sulfa pills and powder and were told to sprinkle it on any open wound. [15] The sulfanilamide compound is more active in the protonated form. The drug has very low solubility and sometimes can crystallize in the kidneys, due to its first pK a of around 10.
A Cochrane review found that while it is an effective treatment for shigellosis it also produces more significant adverse effects than other antibiotic drugs. [43] Staphylococcus aureus infections: No: No: No: In vitro and in vivo activity against both non-resistant and methicillin-resistant Staphylococcus aureus (MRSA) infections. [44] [45 ...
Sulfadimidine or sulfamethazine is a sulfonamide antibacterial.. There are non-standardized a abbreviations for it as "sulfadimidine" (abbreviated SDI [1] [2] and more commonly but less reliably b SDD [3] [4]) and as "sulfamethazine" (abbreviated SMT [5] [6] and more commonly but less reliably c SMZ [7] [8]).
The solution left after removal of the insoluble calcium carbonate still contained some soda. [7] Boric acid (4%) was then added as a buffering agent to maintain a pH of between 9 and 10. Dakin found that alkalinity outside this range was too irritating. [17] The solution, while unstable, remains effective for at least a week, if made to the ...
It is also used in the treatment of Dermatitis herpetiformis, [2] where it is an alternative therapy to Dapsone. Sulfamethoxypyridazine is supplied as 500mg tablets.
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.