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Pseudoephedrine is excreted through urine, and the concentration in urine of this drug shows a large inter-individual spread; that is, the same dose can give a vast difference in urine concentration for different individuals. [123] Pseudoephedrine is approved to be taken up to 240 mg per day.
In the 1980s, there was a movement to crack down on drug users and dealers by using harsher sentences. This created a rapid increase in the number of people in prison that were abusing drugs. The Department of Corrections implemented many prison-based drug treatment programs to help those with addiction, but the DOC was met with many opposers.
Ephedrine is the precursor of synthetic amphetamines. The diastereomer of ephedrine, pseudoephedrine is found in Ephedra sinica together along with ephedrine. Ephedrine and pseudoephedrine are both generally used for weight reduction and performance enhancement. They can also be reduced to methamphetamine. [2]
Ephedrine, pseudoephedrine, and phenylpropanolamine are precursor chemicals used in the illicit manufacture of methamphetamine or amphetamine. They are also common ingredients used to make cough, cold, and allergy products. It was argued that the CMEA would curtail the clandestine production of methamphetamine.
Article 20 mandates drug treatment, education, and prevention measures and requires Parties to assist efforts to "gain an understanding of the problems of abuse of psychotropic substances and of its prevention" and to "promote such understanding among the general public if there is a risk that abuse of such substances will become widespread ...
Illicit methamphetamine is more commonly made by the reduction of ephedrine or pseudoephedrine, which produces the more active d-methamphetamine isomer. The maximum conversion rate for ephedrine and pseudoephedrine is 92%, although typically, illicit methamphetamine laboratories convert at a rate of 50% to 75%. [104]
Over the past quarter century, Slattery’s for-profit prison enterprises have run afoul of the Justice Department and authorities in New York, Florida, Maryland, Nevada and Texas for alleged offenses ranging from condoning abuse of inmates to plying politicians with undisclosed gifts while seeking to secure state contracts.
Government changed policy of sale of legal drugs, which contain substances needed for meth production - the buyer must have a medical prescription, must identify themself by ID card and can obtain only a small quantity. Due to this Czech meth producers are buying drugs with Pseudoephedrine in Poland, where there are no such restrictions. [8]