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Misoprostol is used for the prevention of NSAID-induced gastric ulcers.It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell.
Horse ointment, known as horse oil and horse fat, is a topical formulation derived from subcutaneous fat of horses. [1] Due to its thickness and viscosity , horse ointment is intended for topical use on human skin and mucous membranes to moisturize and increase the restoration of damaged skin.
Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3] Synthetic oxytocin , which is routinely used safely during term labor , is also commonly used to induce abortion in the second or third trimester .
Mifepristone combined with misoprostol is the preferred medication regimen for management of early pregnancy loss. While misoprostol alone can be used, the addition of a dose of mifepristone twenty-four hours before misoprostol administration improves treatment efficacy. [30]
Alprostadil and misoprostol are synthetic forms of prostaglandin E1 used as medications. Lubiprostone , a derivative of prostaglandin E1, is also used as a medication. [ 2 ] [ 3 ] Prostaglandin E 1 is a vasodilator .
The American College of Rheumatology and a Canadian consensus report both recommend GI-protective agents such as misoprostol be combined with long term NSAID therapy and a review concluded that diclofenac/misoprostol is a cost effective treatment in patients requiring long term NSAID therapy who are at increased risk of developing gastropathy. [4]
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References A ace Slang for the drug acepromazine or acetyl promazine (trade names Atravet or Acezine), which is a sedative : 3 commonly used on horses during veterinary treatment, but also illegal in the show ring. Also abbreviated ACP. action The way a horse elevates its legs, knees, hock, and feet. : 3 Also includes how the horse uses its shoulder, humerus, elbow, and stifle; most often used ...
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