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[2] [specify] Using the spray or inhaler at higher than recommended doses or with other corticosteroids can increase the risk for serious, systemic corticosteroid induced side effects. [2] [3] These side effects include weakened immune system, increased risk of systemic infections, osteoporosis, and elevated pressure in the eyes. [19]
Fluticasone furoate, sold under the brand name Flonase Sensimist among others, is a corticosteroid for the treatment of non-allergic and allergic rhinitis administered by a nasal spray. [9] It is also available as an inhaled corticosteroid to help prevent and control symptoms of asthma .
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
Drug Information Portal. U.S. National Library of Medicine. "Mometasone furoate". Drug Information Portal. U.S. National Library of Medicine. Clinical trial number NCT02631551 for "Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-301)" at ClinicalTrials.gov
[3] [2] [4] [6] It is on the World Health Organization's List of Essential Medicines . [ 7 ] In 2022, it was the 25th most commonly prescribed medication in the United States, with more than 22 million prescriptions, [ 8 ] [ 9 ] although it is also sold over-the-counter (OTC).
Flunisolide nasal spray is absorbed into the circulatory system (blood). [3] Corticosteroid nasal sprays may affect the hypothalamic-pituitary-adrenal axis function in humans. [ 7 ] After obtaining the desired clinical effect, the maintenance dose should be reduced to the smallest amount required to control the symptoms.