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Mucociliary clearance has a major role in pulmonary hygiene. MCC effectiveness relies on the correct properties of the airway surface liquid produced, both of the periciliary sol layer and the overlying mucus gel layer, and of the number and quality of the cilia present in the lining of the airways. [3] An important factor is the rate of mucin ...
The respiratory epithelium functions to moisten and protect the airways. It acts as a physical barrier to pathogens, as well as their removal in the mechanism of mucociliary clearance. The ciliated cells are the primary components in the mucociliary clearance mechanism.
These beat rhythmically out from the lungs, moving secreted mucus foreign particles toward the laryngopharynx upwards and outwards, in a process called mucociliary clearance, preventing mucus accumulation in the lungs. Macrophages in the alveoli are part of the immune system which engulf and digest any inhaled harmful agents.
Mucociliary escalator, [4] surfactant, [3] defensins [3] Nasopharynx: Mucus, saliva, lysozyme [3] Eyes: Tears [3] Blood–brain barrier: endothelial cells (via passive diffusion/ osmosis & active selection). P-glycoprotein (mechanism by which active transportation is mediated)
Mucokinetics: increase mucociliary transport (clearance) and transportability of mucus by cough [2] Mucoregulators: suppress underlying mechanisms of mucus hypersecretion [2] Alternatively, attacking the affinity between secretions and the biological surfaces is another avenue, which is used by abhesives and surfactants. [citation needed]
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The relationship escalator, coined by Amy Gahran, describes the traditional order of steps a relationship is expected to take, from monogamy to marriage.
Atypical presentation is common in the elderly. Older patients may have impaired T cell function and hence, they may be unable to mount a febrile response. The mucociliary clearance of older people is also impaired, resulting in diminished sputum production and cough. Therefore, they can present non-specifically with different geriatric ...