Search results
Results from the WOW.Com Content Network
Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes, and serine proteases. [4] It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest. The benzamidine moiety is also found in some pharmaceuticals, such as dabigatran.
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO.It is the simplest amide derivative of benzoic acid.In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5]
Benzidine is prepared in a two step process from nitrobenzene. First, the nitrobenzene is converted to 1,2-diphenylhydrazine, usually using iron powder as the reducing agent. Treatment of this hydrazine with mineral acids induces a rearrangement reaction to 4,4'-benzidine. Smaller amounts of other isomers are also formed. [3]
The ouzo effect during the preparation of absinthe. The ouzo effect (/ ˈ uː z oʊ / OO-zoh), also known as the louche effect (/ l uː ʃ / LOOSH) and spontaneous emulsification, is the phenomenon of formation of a milky oil-in-water emulsion when water is added to ouzo and other anise-flavored liqueurs and spirits, such as pastis, rakı, arak, sambuca and absinthe.
A chain reaction is an example of a complex mechanism, in which the propagation steps form a closed cycle. In a chain reaction, the intermediate produced in one step generates an intermediate in another step. Intermediates are called chain carriers. Sometimes, the chain carriers are radicals, they can be ions as well.
Cascade reactions are often key steps in the efficient total synthesis of complex natural products. The key step in Heathcock's synthesis of dihydroprotodaphniphylline features a highly efficient cascade involving two aldehyde/amine condensations, a Prins-like cyclization, and a 1,5-hydride transfer to afford a pentacyclic structure from an acyclic starting material.
Image credits: National Geographic #5. The 'Spanish Flu' actually likely got its start in Kansas, USA. It's only called the Spanish Flu because most countries involved in WWI had a near-universal ...
Water hydrolyzes formamide to give ammonium formate, which acts as a reducing agent and adds on to the N-formyl derivative. Hydride shift occurs, resulting in loss of carbon dioxide. An ammonium ion is added forming an imine and releasing ammonia. The imine goes through hydrolysis to form the amine, which is depicted in the scheme below.