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Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice . [ 2 ] It is also in flea and tick killing products for pets.
Myristic acid (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH 3 (CH 2) 12 COOH.Its salts and esters are commonly referred to as myristates or tetradecanoates.
Phorbol is a natural product found in many plants, especially those of the Euphorbiaceae and Thymelaeaceae families. [10] [11] Phorbol is the active constituent of the highly toxic New World tropical manchineel or beach apple, Hippomane mancinella. [12]
5366 n/a Ensembl ENSG00000141682 n/a UniProt Q13794 n/a RefSeq (mRNA) NM_021127 n/a RefSeq (protein) NP_066950 NP_001369544 NP_001369545 NP_001369546 NP_001369547 NP_001369552 n/a Location (UCSC) Chr 18: 59.9 – 59.9 Mb n/a PubMed search n/a Wikidata View/Edit Human Phorbol-12-myristate-13-acetate-induced protein 1 is a protein that in humans is encoded by the PMAIP1 gene, and is also known ...
In 1982, Koiti Titani's lab identified an "N-terminal blocking group" on the catalytic subunit of cyclic AMP-dependent protein kinase in cows as n-tetradecanoyl. [6]Almost simultaneously in Claude B. Klee's lab, this same N-terminal blocking group was further characterized as myristic acid. [7]
1-Tetradecanol may be prepared by the hydrogenation of myristic acid (or its esters); myristic acid itself can be found in nutmeg (from where it gains its name) but is also present in palm kernel oil and coconut oil and it is from these that the majority of 1-tetradecanol is produced. [3]
Isopropylamine can be obtained by reaction of isopropyl alcohol with ammonia in presence of a catalyst: [3] (CH 3) 2 CHOH + NH 3 → (CH 3) 2 CHNH 2 + H 2 O. Isopropylamine is a building block for the preparation of many herbicides and pesticides including atrazine, bentazon, glyphosate, imazapyr, ametryne, desmetryn, prometryn, pramitol, dipropetryn, propazine, fenamiphos, and iprodione. [3]
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