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Xylazine was discovered as an antihypertensive agent in 1962 by Farbenfabriken Bayer in Leverkusen, Germany. [1] Accounts of the actions and uses of xylazine in animals were reported as early as the late 1960s and early 1970s. [1] Results from early human clinical studies confirmed that xylazine has several central nervous system depressant ...
Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. [4] While it may be used during pregnancy, it is not recommended for use during breastfeeding. [4] Praziquantel is in the anthelmintic class of medications. [3] It works partly by affecting the function of the worm's sucker. [3]
4‑Hydroxyacetamide (1) is alkylated with n-propyl bromide in the presence of potassium hydroxide to give the ether (2).Nitration of this product with nitric and sulfuric acids proceeds at the position ortho to the amide group (3), which is then reduced with SnCl 2 to yield the phenylenediamine derivative (4).
Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice. It comes under the chemical class of the benzimidazoles. This drug is barely used in horses, [3] goats, sheep, and cattle. It is very scarcely applied on dogs and cats. The drug for livestock is majorly available in the form of pills, tablets, drenches, bolus, etc.
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
However, since some of them can cause health disorders and some also pose a potential danger to humans, regular worming treatments for dogs are quite sensible. In particular, dogs in larger holdings, young animals, dogs in contact with other animals, hunting dogs, strays, and animals fed raw meat products are at higher risk of infection. [69]
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