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Rob Knight (born 1976–77) [1] is a computational microbiologist and professor at the University of California, San Diego. His research involves the development of laboratory and computational techniques to characterize the microbiomes of humans , animals, and the environment.
She went on to complete her doctoral work at the University of Colorado Boulder studying under Rob Knight, who is the founder of the American Gut Project. [2] At the time of her doctoral research, little was known about the microbiome (genes of the bacteria, archaea, microscopic eukaryotes, and viruses interacting in an environment) of the gut ...
Jeffrey Dean Leach (born 1967 in Boston, Texas, known as Jeff Leach) is an American businessman and microbiome researcher from Texas. [1] He is known for his work on the gut microbiome of the Hadza hunter gatherers, [2] founding the Human Food Project, publishing archeology magazines, deceptive business practices, being accused of sexual assault, and founding the Naked Pizza restaurant chain.
The gut has taken the microbiome spotlight because it houses the highest proportion of bacteria. We likely have 1,000 or so species, and maybe up to 100 trillion individual critters in total ...
PICRUSt [1] is a bioinformatics software package. The name is an abbreviation for Phylogenetic Investigation of Communities by Reconstruction of Unobserved States.. The tool serves in the field of metagenomic analysis where it allows inference of the functional profile of a microbial community based on marker gene survey along one or more samples.
UniFrac, a shortened version of unique fraction metric, is a distance metric used for comparing biological communities.It differs from dissimilarity measures such as Bray-Curtis dissimilarity in that it incorporates information on the relative relatedness of community members by incorporating phylogenetic distances between observed organisms in the computation.
Researchers with the American Gut Project and Human Microbiome Project found that twelve microbe families varied in abundance based on the race or ethnicity of the individual. The strength of these associations is limited by the small sample size: the American Gut Project collected data from 1,375 individuals, 90% of whom were white. [56]
National Institutes of Health Director's Pioneer Award is a research initiative first announced in 2004 designed to support individual scientists' biomedical research. The focus is specifically on "pioneering" research that is highly innovative and has a potential to produce paradigm shifting results.