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Caesium in the body has a biological half-life of about one to four months. Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years. Cadmium in bone has a biological half-life of about 30 years.
Methotrexate, formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. [4] It is used to treat cancer , autoimmune diseases , and ectopic pregnancies . [ 4 ] Types of cancers it is used for include breast cancer , leukemia , lung cancer , lymphoma , gestational trophoblastic disease , and osteosarcoma . [ 4 ]
Yellapragada Subbarow [a] (12 January 1895 – 8 August 1948) was an Indian American biochemist who discovered the function of adenosine triphosphate (ATP) as an energy source in the cell, [1] developed methotrexate for the treatment of cancer and led the department at Lederle laboratories in which Benjamin Minge Duggar discovered chlortetracycline in 1945.
Elimination half-life: 3.5 h to 9.2 h, young adults; 4.7 h to 8.6 h, elderly (mean age 72) ... Toxicity to methotrexate is more likely if ketorolac is taken at the ...
The approximate time it takes putrefaction to occur is dependent on various factors. Internal factors that affect the rate of putrefaction include the age at which death has occurred, the overall structure and condition of the body, the cause of death, and external injuries arising before or after death.
Escitalopram has a half-life of 27 to 32 hours. In other words, if you take a dose of 10mg of Lexapro, only 5mg will remain in your bloodstream after 27 to 32 hours.
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2] [3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning.
Changes to a body occurring after death (post-mortem changes) include: [3] Algor mortis: body cooling; Livor mortis: settling of blood in the lowest-placed parts of the body; Rigor mortis: stiffening of limbs. Conditions at the scene of death affect the estimation of time of death.