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Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. [5] Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for ST2 , an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and group 2 innate ...
Interleukin 10 (IL-10) is a protein that inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T cells. In structure, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulphide bonds. [33]
Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter. They are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of ...
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
The skin is one of the largest organs of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5 to 2 m 2 of surface area. [1] 3D still showing human integumentary system. The skin (integument) is a composite organ, made up of at least two major layers of tissue: the epidermis and the dermis. [2]
Melanocytes are melanin-producing neural crest-derived [3] cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), [4] the inner ear, [5] vaginal epithelium, [6] meninges, [7] bones, [8] and heart found in many mammals and birds. [9]
The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
Skin anatomy refers to the structure of the skin, one of the organs of the body. Subcategories. This category has the following 2 subcategories, out of 2 total. A.