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Erythroderma is an inflammatory skin disease with redness and scaling that affects nearly the entire cutaneous surface. [ 1 ] [ 2 ] This term applies when 90% or more of the skin is affected. In ICD-10 , a distinction is made between "exfoliative dermatitis" at L26, and "erythroderma" at L53.9.
Psoriatic erythroderma can be congenital or secondary to an environmental trigger. [12] [13] [14] Environmental triggers that have been documented include sunburn, skin trauma, psychological stress, systemic illness, alcoholism, drug exposure, chemical exposure (e.g., topical tar, computed tomography contrast material), and the sudden cessation of medication.
Ritter's disease of the newborn is the most severe form of SSSS, with similar signs and symptoms. SSSS often includes a widespread painful erythroderma, often involving the face, diaper, and other intertriginous areas. Extensive areas of desquamation might be present. Perioral crusting and fissuring are seen early in the course.
Small plaque parapsoriasis characteristically occurs with skin lesions that are round, oval, discrete patches or thin plaques, mainly on the trunk. [2]: 452 [3]: 207 [4]
The British National Formulary (BNF) is a United Kingdom (UK) pharmaceutical reference book that contains a wide spectrum of information and advice on prescribing and pharmacology, along with specific facts and details about many medicines available on the UK National Health Service (NHS).
Generalized erythroderma – redness of the skin [3] Lymphadenopathy – swollen, enlarged lymph nodes [3] Atypical T cells – malignant lymphocytes known as "Sézary cells" seen in the peripheral blood with typical cerebriform nuclei (brain-shaped, convoluted nuclei) [8] [3] Hepatosplenomegaly– enlarged liver and spleen [9]
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Erythema gyratum repens characteristically presents as wavy red lines on the skin. [1] These regular whirly rings rapidly and repetitively appear within existing ones, expanding outward at a rate of up to 1cm a day, giving the impression that the rash is moving. [3]