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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    The FDA (U.S. Food and Drug Administration) suggests taking Cialis at a maximum as-needed dosage of 10 milligrams no more than once per 72 hours — or a daily dosage of 2.5 milligrams — if you ...

  3. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    For Daily Tadalafil Dosing: 2.5mg and 5mg Tadalafil While tadalafil is available as-needed, it’s also available for once-daily use in much smaller dosages for always-on preparedness for intimate ...

  4. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/lifestyle/safe-cialis-daily...

    Unlike other ED medications, such as Viagra® (sildenafil) and Levitra® (vardenafil), which work for four to five hours per dose, Cialis® (which contains the active ingredient tadalafil) is a ...

  5. Tadalafil - Wikipedia

    en.wikipedia.org/wiki/Tadalafil

    Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]

  6. What Happens If You Take Viagra and You Don't Need It? - AOL

    www.aol.com/happens-viagra-dont-105800158.html

    If you struggle with ED, drugs like Viagra®, sildenafil, tadalafil, and other FDA-approved medications could help with your performance. But if you’re not prescribed one of these meds, taking ...

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Tadalafil is the most versatile inhibitor and has the longest half-life, 17.5 hours. This allows for a longer therapeutic window and is therefore often a more convenient drug than others with a shorter therapeutic window.

  8. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed. ... You should also avoid fatty foods when taking Viagra, ...

  9. List of 5α-reductase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_5α-reductase...

    This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

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