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In the United States, the incidence of cryptococcosis is estimated to be about 0.4-1.3 cases per 100,000 population and 2-7 cases per 100,000 in people affected with AIDS with a case fatality ratio of about 12%. Since 1990 the incidence of AIDs-associated cryptococcosis has fallen by 90% due to the proliferation of antiretroviral therapy.
Cryptococcus is a genus of fungi in the family Cryptococcaceae that includes both yeasts and filamentous species. The filamentous, sexual forms or teleomorphs were formerly classified in the genus Filobasidiella , while Cryptococcus was reserved for the yeasts.
Cryptococcus neoformans is an encapsulated basidiomycetous yeast [1] belonging to the class Tremellomycetes and an obligate aerobe [2] that can live in both plants and animals. Its teleomorph is a filamentous fungus , formerly referred to Filobasidiella neoformans .
Solicoccozyma terrea (synonym Cryptococcus terreus) is a species of fungus in the family Piskurozymaceae. It is only known from its yeast state. In this state, it can use glucose, lactose, galactose and potassium nitrate. The cells are oval with mucous capsules. Cultures of the yeast are cream at first, becoming tan with a “tough” surface skin.
Cryptococcus gattii, formerly known as Cryptococcus neoformans var. gattii, is an encapsulated yeast found primarily in tropical and subtropical climates. Its teleomorph is Filobasidiella bacillispora , a filamentous fungus belonging to the class Tremellomycetes .
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Papiliotrema laurentii (synonym Cryptococcus laurentii) is a species of fungus in the family Rhynchogastremaceae.It is typically isolated in its yeast state.. In its yeast state, it is a rare human pathogen, able to provoke a skin condition, [1] or fungemia in immunocompromised hosts.
Cryptococcus ater is a species of Cryptococcus that has some unique characteristics. When grown on agar it typically produces cream colonies, however when grown on neopeptone agar slants, the colonies turn olive green after approximately four weeks.