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A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al. through the removal and culturing of cancerous lung tissue in the explanted tumor of a 58-year-old caucasian male. [1]
A549 cells share the same characteristics with the alveolar type II cells. This are type II pneumocytes crucial for lung homeostasis, and regeneration upon damage. For research purposes to unravel different molecular mechanisms leading to lung diseases, A549 cells serves as a good model to which translational research can be relied upon.
This page was last edited on 23 November 2019, at 17:55 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
A549: Human: Lung: Human alveolar adenocarcinoma cell line - A549 cultured by MLM at different time points and cell numbers. [8] Immunohistochemistry (IHC) reveals epithelial markers on A549 after culturing in 3D with the MLM. Type II alveolar [8] Primary: Human: Lung: Human tracheal smooth muscle cells (HTSMCs) [8] Primary: Human: Lung
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