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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    The monitoring of warfarin and keeping the international normalized ratio (INR) between 2.0 and 3.0, along with avoiding over and under treatment, has driven a search for an alternative. [3] [14] A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15]

  3. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is a highly selective, orally bioavailable, and reversible direct inhibitor of free and clot-bound factor Xa. Factor Xa catalyzes the conversion of prothrombin to thrombin, the final enzyme in the coagulation cascade that is responsible for fibrin clot formation. [ 28 ]

  4. Low-molecular-weight heparin - Wikipedia

    en.wikipedia.org/wiki/Low-molecular-weight_heparin

    Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. [1] They are used in the prevention of blood clots and, in the treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism), and the treatment of myocardial infarction.

  5. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.

  6. FACT CHECK: Are Voters In Kentucky Having Their Votes ... - AOL

    www.aol.com/fact-check-voters-kentucky-having...

    The machine was temporarily taken out of service, and the voter was eventually able to vote for their preferred candidate. Fact Check: A post going viral on X claims to show a voting machine i.

  7. The Fight to Free Kidney Dialysis Patients From Their Bulky ...

    www.aol.com/fight-free-kidney-dialysis-patients...

    The machines remain large, loud, and laborious to use. Patients learning to do home dialysis require months of intensive classes to learn the hundreds of steps to connect and disconnect from a ...

  8. FDA approves new pain medication as an alternative to opioids ...

    www.aol.com/fda-approves-pain-medication...

    The FDA on Thursday approved a new class of pain medication that provides an alternative to opioids. It will be sold under the brand name Journavx.

  9. Antipsychotic switching - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic_switching

    In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...