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Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition (1:1,000,000), in which the bones have lesions, inflammation, and pain.It is called multifocal because it can appear in different parts of the body, primarily bones, and osteomyelitis because it is very similar to that disease, although CRMO appears to be without any infection.
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.
The tumor causes a great deal of pain, and can even lead to fracture of the affected bone. As with human osteosarcoma, bone biopsy is the definitive method to reach a final diagnosis. Osteosarcoma should be differentiated from other bone tumours and a range of other lesions, such as osteomyelitis.
Osteomyelitis (OM) is an infection of bone. [1] Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. [1] The feet, spine, and hips are the most commonly involved bones in adults. [2] The cause is usually a bacterial infection, [1] [7] [2] but rarely can be a fungal infection. [8]
Surgery may be required for patients with advanced cases of vertebral osteomyelitis. Spinal fusion is a common approach to destroying the microorganism causing the disease and rebuilding parts of the spine that were lost due to the infection. Fusions can be approached anteriorly or posteriorly, or both, depending on where the infection is ...
Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones. Bone-originating primary tumors such as osteosarcoma , chondrosarcoma , and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [ 1 ]
Spinal nerve compression and weakening of the vertebral structure cause the symptoms. Pain is the most common symptom at presentation. [ 1 ] [ 3 ] [ 7 ] Other common symptoms of spinal cord compression include muscle weakness, sensory loss , numbness in hands and legs, and rapid onset paralysis .
Or, tuberculosis, syphilis, and brucellosis are also known to cause myelitis in immune-compromised individuals. Myelitis is a rare manifestation of bacterial infection. Fungal myelitis: Fungi have been reported to cause spinal cord disease either by forming abscesses inside the bone or by granuloma.