Search results
Results from the WOW.Com Content Network
Leflunomide, sold under the brand name Arava among others, is an immunosuppressive disease-modifying antirheumatic drug , [8] used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase. [9] Bottle of Leflunomide (Arava) and tablet
Swelling in legs, arms, feet or hands. Distended abdomen. Puffy, dough-like skin. ... Damage to the capillaries or leaky capillary syndrome can also cause swelling of the extremities, ...
Other studies have also shown that this condition may affect women more than men, as women may experience swelling due to fluid retention in the legs, feet or abdomen after being stationary. [4] The proposed mechanism includes the possibility that increased leg fat may impair the ability to dissipate heat. [ 4 ]
Individuals affected by RS3PE typically have repeated episodes of inflammation of the lining of their synovial joints and swelling of the end portion of the limbs. [8] The arms and hands are more commonly affected than the legs and feet. [8] Both sides are usually involved though RS3PE can affect only one side in certain cases. [8]
Causes of edema that are generalized to the whole body can cause edema in multiple organs and peripherally. For example, severe heart failure can cause pulmonary edema, pleural effusions, ascites and peripheral edema. Such severe systemic edema is called anasarca. In rare cases, a parvovirus B19 infection may cause generalized edemas. [9]
Allergic reactions are a relatively common cause of throat swelling in general, but sometimes the uvula can be affected alone. “This is known as uvular angioedema,” says Dr. Morrison.
Lymphedema can also be categorized by its severity (usually compared to a healthy extremity): [46] Grade 1 (mild edema): Involves the distal parts such as a forearm and hand or a lower leg and foot. The difference in circumference is less than 4 cm (1.6 in) and no other tissue changes are present.
That’s because diet can influence key aging mechanisms like inflammation, cellular repair, and insulin sensitivity. These all play critical roles in determining lifespan, explains Dr. Darshan ...