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Pernicious anemia is the most common cause of vitamin B 12 deficiency anemia in adults, which results from malabsorption of vitamin B 12 due to a lack or loss of intrinsic factor. [ 2 ] [ 8 ] There are relatively few studies which have assessed the impact of haematological measures in response to B 12 supplementation.
Malabsorption. There are a few reasons your body may not be able to absorb sufficient amounts of B12. If you’ve had gastric bypass surgery, your new alimentary pathway may bypass the section of ...
Other causes of B12 malabsorption include intrinsic factor deficiency, pernicious anemia, bariatric surgery pancreatic insufficiency, obstructive jaundice, tropical sprue and celiac disease, and radiation enteritis of the distal ileum. [118] Age can be a factor.
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Fortunately, though, vitamin B12 isn't so hard to get enough of because it's so widely dispersed in the food supply and daily needs are relatively low. As vitamins go, vitamin B12 is a pretty ...
Vitamin B12 deficiency causes symptoms like fatigue, poor memory, a swollen tongue, and canker sores.
Malabsorption is a state arising from abnormality in absorption of food nutrients across ... Other Possible Causes. ... (such as anaemia with vitamin B12 malabsorption).
Imerslund–Gräsbeck syndrome is a rare autosomal recessive, familial form of vitamin B12 deficiency caused by malfunction of the "Cubam" receptor located in the terminal ileum. This receptor is composed of two proteins, amnionless (AMN), and cubilin. A defect in either of these protein components can cause this syndrome.
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