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Hyperammonemia, or high ammonia levels, is a metabolic disturbance characterised by an excess of ammonia in the blood. Severe hyperammonemia is a dangerous condition that may lead to brain injury and death. It may be primary or secondary. Ammonia is a substance that contains nitrogen. It is a product of the catabolism of protein.
Hyperammonemia occurs when the body produces excess ammonia. This ammonia primarily exists as ammonium ion that has a concentration less than or around 35 μmol/L in normal referenced serum levels. [3] Excess ammonia is processed in the liver through the urea cycle to produce urea. [3]
The resultant effect of this toxicity can be reduced brain energy metabolism and function. Importantly, the toxic effects of ammonia on astrocyte remodeling can be reduced through administration of L-carnitine. [89] This astrocyte remodeling appears to be mediated through ammonia-induced mitochondrial permeability transition.
The size of the brain is a frequent topic of study within the fields of anatomy, biological anthropology, animal science and evolution.Measuring brain size and cranial capacity is relevant both to humans and other animals, and can be done by weight or volume via MRI scans, by skull volume, or by neuroimaging intelligence testing.
Mass effect such as brain tumor, infarction with edema, contusions, subdural or epidural hematoma, or abscesses all tend to deform the adjacent brain. [citation needed] Generalized brain swelling can occur in ischemic-anoxia states, acute liver failure, [9] hypertensive encephalopathy, hypercarbia (hypercapnia), and Reye hepatocerebral syndrome ...
For some time now, research has shown the importance of certain vitamins and how they contribute to our brain function. And with the number of people with dementia rapidly increasing in the U.S ...
Clemson’s group of senior day honorees will be bigger than normal against the Citadel. The Tigers end their home schedule against the FCS opponent on Saturday before a road game at South ...
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