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This mechanical theory is supported by the fact that histological findings of the Modic Changes demonstrate disruption of the endplates with evidence of chronic inflammation. This in turn suggests that this erosion weakens the bone matrix, giving rise to stress fractures and consequent oedema.
Precautionary low back screening by a mechanical pain expert is rarely done - and it’s one of the biggest reasons I see for knee pain misdiagnosis. ... which can lead to pain, inflammation, and ...
Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; hyper from Greek ὑπέρ (huper) 'over' + -algesia from Greek ἄλγος (algos) 'pain') is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.
Morning stiffness that improves later in the day is a common feature (this implies inflammatory-type joint pain versus mechanical-type joint pain). [citation needed] Swelling and pain usually result in limited movement of the affected joints, for example a knee held bent causing a limp, or being unable to make a full fist.
Treating the pain with anti-inflammatory drugs and steroids like dexamethasone and diclofenac, also produced the same result, although they were effective against pain early on.
Irritation, in biology and physiology, is a state of inflammation or painful reaction to allergy or cell-lining damage. A stimulus or agent which induces the state of irritation is an irritant . Irritants are typically thought of as chemical agents (for example phenol and capsaicin ) but mechanical, thermal (heat), and radiative stimuli (for ...
Arthritis is a form of arthropathy that involves inflammation of one or more joints, [3] [4] while the term arthropathy may be used regardless of whether there is inflammation or not. Joint diseases can be classified as follows: [citation needed] Arthritis; Infectious arthritis; Septic arthritis (infectious) Tuberculosis arthritis; Reactive ...
Injury can be described as a ‘mechanical disruption of tissues resulting in pain.' [13] Despite the fact tissues can self-repair, muscle degradation occurs after repeated and prolonged use. [13] Overuse and strain injuries can occur at work, physical activity and daily life. [11]