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This image is a derivative work of the following images: File:DNA_replication_en.svg licensed with PD-user . 2009-06-01T14:09:19Z Bibi Saint-Pol 691x336 (113021 Bytes) {{Information |Description= {{en|DNA replication or DNA synthesis is the process of copying a double-stranded DNA molecule.
Eukaryotes initiate DNA replication at multiple points in the chromosome, so replication forks meet and terminate at many points in the chromosome. Because eukaryotes have linear chromosomes, DNA replication is unable to reach the very end of the chromosomes. Due to this problem, DNA is lost in each replication cycle from the end of the chromosome.
The process of semiconservative replication for the site of DNA replication is a fork-like DNA structure, the replication fork, where the DNA helix is open, or unwound, exposing unpaired DNA nucleotides for recognition and base pairing for the incorporation of free nucleotides into double-stranded DNA. [3]
The factual accuracy of this diagram or the file name is disputed. ... DNA replication or DNA synthesis is the process of copying a double-stranded DNA molecule.
We also know that the replication-timing program changes during development, along with changes in the expression of genes. For many decades now, it has been known that replication timing is correlated with the structure of chromosomes. For example, female mammals have two X chromosomes. One of these is genetically active, while the other is ...
The DNA re-replication response is different from the response taken when damage is due to oxygen radical generation. Damage from oxygen radical generations leads to a response from the Myc oncogene, which phosphorylates p53 and H2AX. [16] The ATM/ATR DNA damage network will also respond to cases where there is an overexpression of Cdt1.
Stylized DNA replication fork with nucleotides matched, 5'->3' synthesis shown, no enzymes in diagram. Please credit Madeleine Price Ball if used in a commercial context.
DNA is a duplex formed by two anti-parallel strands. Following Meselson-Stahl, the process of DNA replication is semi-conservative, whereby during replication the original DNA duplex is separated into two daughter strands (referred to as the leading and lagging strand templates). Each daughter strand becomes part of a new DNA duplex.
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