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As human and bacteria both have ribosomes, streptomycin has significant side effects in humans. At low concentrations, however, streptomycin inhibits only bacterial growth. [18] Streptomycin is an antibiotic that inhibits both Gram-positive and Gram-negative bacteria, [19] and is therefore a useful broad-spectrum antibiotic.
Streptomycin is the first-in-class aminoglycoside antibiotic. It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis . Streptomycin lacks the common 2-deoxystreptamine moiety (image right, below) present in most other members of this class.
Aminoglycosides are a class of antibiotics. The most frequently used aminoglycosides include gentamicin, amikacin and streptomycin. These antibiotics are usually used in combination with other antimicrobial agents to treat drug-resistant organisms. For example, they are used with β-lactam for bacterial infections in pneumonia. [7]
Aminoglycoside. The standard treatment is with a minimum of four weeks of high-dose intravenous penicillin with an aminoglycoside such as gentamicin. The use of high-dose antibiotics is largely based upon animal models. [2] Leo Loewe of Brooklyn Jewish Hospital was the first to successfully treat subacute bacterial endocarditis with penicillin ...
Tetracyclines, rifampicin, and the aminoglycosides streptomycin and gentamicin: Yes [5] Yersinia pestis: Bubonic plague: Culture Aminoglycosides such as streptomycin and gentamicin, tetracyclines (especially doxycycline), and the fluoroquinolone ciprofloxacin: Under research [6] usually Burkholderia cepacia and other Burkholderia species ...
This involves the administration of a broad-spectrum antibiotic based on the signs and symptoms presented and is initiated pending laboratory results that can take several days. [34] [35] When the responsible pathogenic microorganism is already known or has been identified, definitive therapy can be started. This will usually involve the use of ...
It is not recommended with streptomycin or other medications that may damage the auditory vestibular nerve. [1] It is not recommended during pregnancy as it may cause kidney or hearing problems in the baby. [1] Capreomycin is commonly grouped with the aminoglycoside family of medications. [2] How it works is unclear. [1]
For this reason, oral surgeons often prescribe a short course of antibiotics to be taken a few days before to a few days after oral surgery. Once an infection has occurred, treatment is much more complicated and generally involves the administration of several weeks of penicillin and aminoglycoside antibiotics. [citation needed]