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Hyperandrogenism has also been observed to increase insulin tolerance, which can lead to type two diabetes and dyslipidemia, such as high cholesterol. These effects may have psychological impacts, sometimes leading to social anxiety and depression, especially in adolescent girls and young women.
Obesity is the chief symptom of HAIR-AN. [4] In the majority of young women affected by HAIR-AN, hyperandrogenism leads to oily skin, acne, hirsutism, menstrual irregularities and, in some cases, androgenic alopecia, clitoromegaly, changes in muscle mass and deepening of the voice.
In 2013 Indian government introduced 'hyperandrogenism regulations' [10] more restrictive than those published by the IAAF. These regulations stated that "intersex female sports persons with elevated androgen production give rise to a particular concern".
This graph of "Acceptable Testosterone Levels in Females and Males Compared to a Hypothetical Athlete" shows a situation in which the hypothetical athlete above may be a female with hyperandrogenism, higher than normal levels of testosterone, and would be subjected to sex verification tests and possibly forced to undergo aggressive medical protocols.
Hypergonadism is a condition where there is a hyperfunction of the gonads. [1] It can manifest as precocious puberty, and is caused by abnormally high levels of testosterone or estrogen, crucial hormones for sexual development.
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
President Donald Trump signs an executive order barring transgender female athletes from competing in women's or girls' sporting events, in the East Room of the White House, Wednesday, Feb. 5 ...
[93] [115] [95] [101] In any case, besides the study of bicalutamide as a puberty blocker in transgender girls, it has been found to be effective as an antiandrogen in women with hirsutism due to hyperandrogenism [60] [61] [64] and in boys with gonadotropin-independent precocious puberty, [116] [117] [118] [100] and demasculinization and ...