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Current Medicinal Chemistry is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Atta-ur-Rahman, FRS (Kings College University of Cambridge Cambridge, UK). The journal covers developments in medicinal chemistry and rational drug design and publishes original research reports and review papers. [2]
Testing of umifenovir's efficacy has mainly occurred in China and Russia, [7] [8] and it is well known in these two countries. [9] Some of the Russian tests showed the drug to be effective against influenza A and a direct comparison with oseltamivir showed similar efficiency in vitro and in a clinical setting.
The mechanism of the HIV protease shares many features with the rest of the aspartic protease family although the full detailed mechanism of this enzyme is not fully understood. [12] The water molecule seems to play a role in the opening and closing of the flaps as well as increasing the affinity between enzyme and substrate.
Current Topics in Medicinal Chemistry is a biweekly peer-reviewed medical journal published by Bentham Science Publishers. It includes review articles on all aspects of medicinal chemistry, including drug design. The current editor-in-chief is Jia Zhou (University of Texas, Medical Branch).
ChemMedChem is a biweekly peer-reviewed scientific journal covering medicinal chemistry.It is published by Wiley-VCH on behalf of Chemistry Europe.In addition to original research in the form of full papers and shorter communications, the journal contains review-type articles (reviews, minireviews, patent reviews, essays, highlights) as well as occasional book reviews and conference reports.
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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use.
Ohmefentanyl (also known as β-hydroxy-3-methylfentanyl, OMF and RTI-4614-4) [1] is an extremely potent opioid analgesic drug which selectively binds to the μ-opioid receptor.