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Retinal pigment epithelium-specific 65 kDa protein (also known as RPE65) is a retinoid isomerohydrolase enzyme of the vertebrate visual cycle. [5] [6] RPE65 is expressed in the retinal pigment epithelium (RPE, a layer of epithelial cells that nourish the photoreceptor cells) and is responsible for the conversion of all-trans-retinyl esters to 11-cis-retinol during phototransduction.
These multiple conversion steps are what make it gentler on the skin. Retinol: The most common form of over-the-counter topical vitamin A products, retinol comes in varying percentages. Those with ...
Retinyl palmitate, or vitamin A palmitate, is the ester of retinol and palmitic acid, with formula C 36 H 60 O 2. It is the most abundant form of vitamin A storage in animals. [2] An alternate spelling, retinol palmitate, which violates the -yl organic chemical naming convention for esters, is also frequently seen.
Vitamin A occurs as two principal forms in foods: A) retinoids, found in animal-sourced foods, either as retinol or bound to a fatty acid to become a retinyl ester, and B) the carotenoids α-carotene (alpha-carotene), β-carotene, γ-carotene (gamma-carotene), and the xanthophyll beta-cryptoxanthin (all of which contain β-ionone rings) that ...
Available in prescription and over-the-counter form in various concentrations and under different names like retinol, retinoic acid, tretinoin, retinyl palmitate, retinyl linoleate and retinyl ...
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes, immune function and reproductive development. [3]
Dermatologists and ELLE editors weigh in on the best retinol body lotions for smoother, firmer, and more radiant skin. Plus, find a range of top-rated, customer-loved picks.
In the human, an example of such a transacylation reaction is that catalyzed by the enzyme LRAT that converts an all-trans retinol to an all-trans-retinyl ester. The latter is a storage form of Vitamin A in various tissues, as well as a retinal precursor in the retina (see visual cycle ).
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