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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
It is often used in combination with other medications. [1] It is believed to work by making airway secretions more liquid. [1] Side effects may include dizziness, sleepiness, skin rash, and nausea. [2] Guaifenesin has been used medically since at least 1933. [3] It is available as a generic medication and an over-the-counter drug. [1] [4]
Patients taking MAO inhibitors can experience a severe hypertensive crisis if given a sympathomimetic drug such as naphazoline HCl; Drug interactions can occur with anaesthetics that sensitize the myocardium to sympathomimetics (e.g. cyclopropane or halothane cautiously) Exercise caution when applying prior to use of phenylephrine.
Phenylephrine is found in a wide range of cold and flu medications, including Sudafed PE, Benadryl Allergy D Plus Sinus and Vicks DayQuil Cold and Flu Relief. Here’s what experts say are ...
On Nov. 7, the Food and Drug administration announced a proposal to remove oral phenylephrine — a decongestant found in products by brands including Sudafed PE, Vicks DayQuil and Theraflu ...
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
[6] [8] The combination of selegiline with certain other medications, like phenylephrine and buspirone, is also warned against for similar reasons. [8] [12] [114] [71] In the case of phenylephrine, this drug is substantially metabolized by monoamine oxidase, including by both MAO-A and MAO-B.
Polypharmacy is most commonly defined as the use of five or more medications daily by an individual. [6] However, the definition of polypharmacy is still debated and can vary from two to 11 concurrent medications. [6] Any drug: Cannabis: Amp joint [7] Any drug: Nicotine: Cooler [5] Any β-Carboline containing plant (e.g. Banisteriopsis caapi or ...
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