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  2. Epiphyseal plate - Wikipedia

    en.wikipedia.org/wiki/Epiphyseal_plate

    The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).

  3. Osteochondritis dissecans - Wikipedia

    en.wikipedia.org/wiki/Osteochondritis_dissecans

    The prognosis is good for stable lesions (stage I and II) in juveniles with open growth plates; treated conservatively—typically without surgery—50% of cases will heal. [68] Recovery in juveniles can be attributed to the bone's ability to repair damaged or dead bone tissue and cartilage in a process called bone remodeling.

  4. Vosoritide - Wikipedia

    en.wikipedia.org/wiki/Vosoritide

    In the European Union, vosoritide is indicated for the treatment of achondroplasia in people two years of age and older whose epiphyses are not closed. [5]In the United States, vosoritide is indicated to increase growth in children five years of age and older with achondroplasia and open epiphyses (growth plates).

  5. Epiphysiodesis - Wikipedia

    en.wikipedia.org/wiki/Epiphysiodesis

    Epiphysiodesis is a pediatric orthopedic surgery procedure that aims at altering or stopping the bone growth naturally occurring through the growth plate also known as the physeal plate. There are two types of epiphysiodesis: temporary hemiepiphysiodesis and permanent epiphysiodesis.

  6. BridgeBio Pharma Announces Publication in the New England ...

    lite.aol.com/tech/story/0022/20241118/9275312.htm

    About Achondroplasia Achondroplasia is the most common cause of disproportionate short stature, affecting approximately 55,000 people in the United States (U.S.) and European Union (EU), including up to 10,000 children and adolescents with open growth plates. Achondroplasia impacts overall health and quality of life, leading to medical ...

  7. Metaphysis - Wikipedia

    en.wikipedia.org/wiki/Metaphysis

    The metaphysis may be divided anatomically into three components based on tissue content: a cartilaginous component (epiphyseal plate), a bony component (metaphysis) and a fibrous component surrounding the periphery of the plate. The growth plate synchronizes chondrogenesis with osteogenesis or interstitial cartilage growth with both ...

  8. Epiphysis - Wikipedia

    en.wikipedia.org/wiki/Epiphysis

    Many bones in the body contain an epiphysis, a region critical for growth and articulation. The humerus, for example, is situated between the shoulder and elbow and contributes significantly to upper limb movement. Below the elbow are the radius and ulna, two bones that run parallel to each other.

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