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SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
Muscle pain (myalgia) is one of the most common side effects in patients right after starting statins, says Sameer Arora, MD, a cardiology fellow at the University of North Carolina at Chapel Hill ...
For this population, some studies have suggested that adding CoQ10 can reduce statin side effects, especially muscle pain associated with statin use, explains VenHuizen.
The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [5] [65] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke, and 5 cases of muscle damage per 10,000 people treated. [34]
The known cardiovascular benefits of atorvastatin over time outweigh the low risk of muscle-related side effects. [63] [62] Statin-induced rhabdomyolysis is rare, occurring in less than 0.1% of people who take statins. [64] [65] [66] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the ...
Part of the power of statins lies in the fact that they cause few side effects. “Generally, about 90 out of 100 people have no trouble with a stain,” says Dr. Blumenthal. ... Part of the power ...
By reducing LDL cholesterol, statins can also help lower a person’s risk for cardiovascular diseases such as heart failure, coronary heart disease, heart attack, and stroke.
Lovastatin and other statins have been studied for their chemopreventive and chemotherapeutic effects. No such effects were seen in the early studies. [16] More recent investigations revealed some chemopreventive and therapeutic effects, for certain types of cancer, especially in combination of statins with other anticancer drugs. [17]
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