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Peptic ulcer disease is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. [ 1 ] [ 7 ] An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
Turck feeds dogs Bacillus coli and produces ulcers. [7] 1907 Berkley Moynihan suggests that acid is a cause of ulcers. [1] 1910 Schwartz publishes the excess acid theory of the ulcer, coining the famous phrase "no acid, no ulcer." [2] Gibelli claims to be unable to reproduce Turck's study where he artificially created ulcers by feeding dogs ...
Valentino's syndrome is pain presenting in the right lower quadrant of the abdomen caused by a duodenal ulcer with perforation through the retroperitoneum. [1]It is named after Rudolph Valentino, an Italian actor, who presented with right lower quadrant pain in New York, which turned out to be a perforated peptic ulcer.
Gastric outlet obstruction (GOO) is a medical condition where there is an obstruction at the level of the pylorus, which is the outlet of the stomach.Individuals with gastric outlet obstruction will often have recurrent vomiting of food that has accumulated in the stomach, but which cannot pass into the small intestine due to the obstruction.
Mucosal disruption in acid peptic disease patients can be caused by infection, barrier disruption, or gastric acid hypersecretion.Acid peptic diseases can arise due to various risk factors such as Helicobacter pylori infection, alcoholism, tobacco use, cocaine and amphetamine use, nonsteroidal anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor ...
Successful eradication regimens have revolutionised the treatment of peptic ulcers. [152] [153] Eradication of H. pylori is also associated with a subsequent decreased risk of duodenal or gastric ulcer recurrence. [135] Plant extracts and probiotic foods are being increasingly used as add-ons to usual treatments.
A peptic ulcer may accompany gastritis. Endoscopic image. Many people with gastritis experience no symptoms at all. However, upper central abdominal pain is the most common symptom; the pain may be dull, vague, burning, aching, gnawing, sore, or sharp. [13]
Anti-ulcer agents are medications or supplements used to cure the damage of mucosal layer on organs to prevent the damage from further extending to deeper regions to cause complications. An anti-ulcer medication for treating mouth ulcer is triamcinolone, a corticosteroid. Other anti-ulcer supplements include vitamin B2 and vitamin B12.