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Atopy, reduced lung function, and respiratory infections in infants with wheeze are risk factors for asthma persistence into adulthood, and a lower lung function and greater magnitude of atopy at this age is associated with more severe disease. [5] Severe atopic asthma is also additionally amenable to anti-immunoglubulin E (IgE) therapy. [4]
The mechanisms behind allergic asthma—i.e., asthma resulting from an immune response to inhaled allergens—are the best understood of the causal factors. In both people with asthma and people who are free of the disease, inhaled allergens that find their way to the inner airways are ingested by a type of cell known as antigen-presenting ...
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...
“Anyone can have an asthma attack, but your risk of an asthma exacerbation is much higher if your asthma is poorly controlled,” says Dr. Mustafa. ... Asthma Attack. Mayo Clinic. Asthma Facts ...
The strongest risk factor for developing asthma is a history of atopic disease; [66] with asthma occurring at a much greater rate in those who have either eczema or hay fever. [80] Asthma has been associated with eosinophilic granulomatosis with polyangiitis (formerly known as Churg–Strauss syndrome), an autoimmune disease and vasculitis . [ 81 ]
Predisposing factors to allergic rhinitis include eczema (atopic dermatitis) and asthma. These three conditions can often occur together which is referred to as the atopic triad . [ 25 ] Additionally, environmental exposures such as air pollution and maternal tobacco smoking can increase an individual's chances of developing allergies.
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