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The submucosa (or tela submucosa) is a thin layer of tissue in various organs of the gastrointestinal, respiratory, and genitourinary tracts. It is the layer of dense irregular connective tissue that supports the mucosa (mucous membrane) and joins it to the muscular layer, the bulk of overlying smooth muscle (fibers running circularly within layer of longitudinal muscle).
The submucosa consists of a dense and irregular layer of connective tissue with blood vessels, lymphatics, and nerves branching into the mucosa and muscular layer. It contains the submucous plexus , and enteric nervous plexus , situated on the inner surface of the muscular layer.
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue .
As its Latin name indicates, it is a characteristic component of the mucosa, or the mucosa's "own special layer." Thus, the term mucosa or mucous membrane refers to the combination of the epithelium and the lamina propria. [1] The connective tissue of the lamina propria is loose and rich in cells.
The mucosa is the innermost layer of the gastrointestinal tract. The mucosa surrounds the lumen, or open space within the tube. This layer comes in direct contact with digested food . The mucosa is made up of: Epithelium – innermost layer. Responsible for most digestive, absorptive and secretory processes.
Submucosal means that the actual gland resides in the connecting tissue below the mucosa. The submucosa is the tissue that connects the mucosa to the muscle outside the tube. The glands themselves are quite complex. The mucus factory is at the bottom, in the submucosa, it is composed of many little sacs (acini) where the mucus originates.
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
The inner part of the stomach wall is the gastric mucosa a mucous membrane that forms the lining of the stomach. the membrane consists of an outer layer of columnar epithelium, a lamina propria, and a thin layer of smooth muscle called the muscularis mucosa. Beneath the mucosa lies the submucosa, consisting of fibrous connective tissue. [17]