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  2. Warfarin - Wikipedia

    en.wikipedia.org/wiki/Warfarin

    Warfarin is indicated for the prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism; [9] prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation and/or cardiac valve replacement; [9] and reduction in the risk of death, recurrent myocardial infarction, and thromboembolic events such as stroke or systemic embolization after ...

  3. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    For many drugs, severe toxicities in humans occur at sublethal doses, which limit their maximum dose. A higher safety-based therapeutic index is preferable instead of a lower one; an individual would have to take a much higher dose of a drug to reach the lethal threshold than the dose taken to induce the therapeutic effect of the drug.

  4. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    Rivaroxaban is taken once daily, and apixaban is taken twice daily. [5] Warfarin, dabigatran, and edoxaban require the use of a parenteral anticoagulant to initiate oral anticoagulant therapy. [ 19 ] [ 125 ] When warfarin is initiated for VTE treatment, a 5-day minimum of a parenteral anticoagulant [ j ] together with warfarin is given, which ...

  5. Iron poisoning - Wikipedia

    en.wikipedia.org/wiki/Iron_poisoning

    Iron poisoning can occur when doses of 20 to 60 mg/kg or more of elemental iron is ingested with most cases reporting primarily gastrointestinal symptoms. [4] Systemic signs and symptoms shown in serious toxicity occur at higher doses exceeding 60 mg/kg. [5] Ingesting above 120 mg/kg may be fatal. [4]

  6. Warfarin necrosis - Wikipedia

    en.wikipedia.org/wiki/Warfarin_necrosis

    Warfarin necrosis is a rare but severe complication of treatment with warfarin or related anticoagulants. [2] The typical patient appears to be an obese, middle aged woman (median age 54 years, male to female ratio 1:3). [1] [3]: 122–3 This drug eruption usually occurs between the third and tenth days of therapy with warfarin derivatives. [1]

  7. Patrick Mahomes reportedly diagnosed with 'mild' high ankle ...

    www.aol.com/sports/patrick-mahomes-reportedly...

    Kansas City Chiefs quarterback Patrick Mahomes has been diagnosed with a "mild" high ankle sprain, according to NFL Network's Ian Rapoport. Mahomes was thought to have sustained some kind of ankle ...

  8. Wendy Williams is 'permanently incapacitated' amid dementia ...

    www.aol.com/wendy-williams-permanently...

    Wendy Williams' health has taken a turn for the worse amid her battle with dementia and aphasia. The former "Wendy Williams Show" host, 60, has become "cognitively impaired and permanently ...

  9. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

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