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Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [ 3 ] [ 4 ] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy . [ 3 ]
Lactitol is listed as an excipient in some prescription drugs. [3] [4]Lactitol is a laxative and is used to prevent or treat constipation, [5] e.g., under the trade name Importal.
Tagatose is a natural sweetener present in only small amounts in fruits, cacao, and dairy products. Starting with lactose, which is hydrolyzed to glucose and galactose, tagatose can then be produced commercially from the resulting galactose. [4]
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Lactulose works by the osmotic effect, which retains water in the colon; lowering the pH through bacterial fermentation to lactic, formic, and acetic acids; and increasing colonic peristalsis. Lactulose is also indicated in portal-systemic encephalopathy.