Search results
Results from the WOW.Com Content Network
Unlike traditional antidepressants that target the neurotransmitters serotonin and/or norepinephrine, ketamine targets glutamate — the most abundant chemical messenger in the brain, Feifel said.
An autopsy report determined that Matthew Perry died of the acute effects of ketamine. ... It also can work in the brain to cause pain relief and lowers heart rate and blood pressure, Alan says ...
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
Ketamine is an anesthetic (tranquilizer) and mental health medication that blocks N-methyl-D-aspartate (NMDA) receptors in the brain. Because of its effects on NMDA, it “can make one experience ...
Ketamine potentiates the sedative effects of propofol [85] and midazolam. [86] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [87] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Ketamine's neuroplasticity-promoting effects strengthen the cognitive restructuring that takes place through traditional psychotherapy, thereby leading to long-lasting behavioural change. [ 4 ] [ 5 ] KAP offers promising directions for research on new antidepressant alternatives, but is still not sufficiently defined or evaluated as a treatment ...
A first-hand review and experience of a person using ketamine therapy to treat anxiety and depression. Discover ketamine therapy side effects and more about Mindbloom.
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.