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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
T4 is capable of undergoing only a lytic life cycle and not the lysogenic life cycle. The species was formerly named T-even bacteriophage, a name which also encompasses, among other strains (or isolates), Enterobacteria phage T2, Enterobacteria phage T4 and Enterobacteria phage T6.
The T4 rII system is an experimental system developed in the 1950s by Seymour Benzer for studying the substructure of the gene. The experimental system is based on genetic crosses of different mutant strains of bacteriophage T4 , a virus that infects the bacteria Escherichia coli .
Lysis inhibition: T4-like phages have two genes, rI and rIII, that inhibit the T4 holin, if the infected cell undergoes super-infection by another T4 (or closely related) virion. Repeated super-infection can cause the T4 infection to continue without lysis for hours, leading to accumulation of virions to levels 10-fold higher than normal.
The prokaryotic cell is shown with its DNA, in green. 2. The bacteriophage attaches and releases its DNA, shown in red, into the prokaryotic cell. 3. The phage DNA then moves through the cell to the host's DNA. 4. The phage DNA integrates itself into the host cell's DNA, creating prophage. 5. The prophage then remains dormant until the host ...
Bacteriophage T4 is a particularly well studied virus and its protein quaternary structure is relatively well defined. [10] A study by Floor (1970) [11] showed that, during the in vivo construction of the virus by specific morphogenetic proteins, these proteins need to be produced in balanced proportions for proper assembly of the virus to occur.
A bacteriophage is a type of virus that infects bacteria. Bacteriophage are likely the most numerous "organisms" on Earth [1] [2] The main article for this category is Bacteriophage .
The isolation of conditional lethal mutants of the bacterial virus T4 (bacteriophage T4) during 1962-1964 by members of the phage group at the California Institute of Technology provided an opportunity to study the function of virtually all of the genes that are essential for growth of the bacteriophage under laboratory conditions. [3]