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  2. Memory T cell - Wikipedia

    en.wikipedia.org/wiki/Memory_T_cell

    Antigen-specific memory T cells specific to viruses or other microbial molecules can be found in both central memory T cells (T CM) and effector memory T cells (T EM) subsets. . Although most information is currently based on observations in the cytotoxic T cells (CD8-positive) subset, similar populations appear to exist for both the helper T cells (CD4-positive) and the cytotoxic T ce

  3. T memory stem cell - Wikipedia

    en.wikipedia.org/wiki/T_memory_stem_cell

    Longitudinal studies on T SCM dynamics in patients undergoing hematopoietic stem cell transplantation (HSCT) have shown that donor-derived T SCM cells were highly enriched early after HSCT, differentiated directly from Tn, and that Tn and T SCM cells (but not central memory or effector T cells) were able to reconstitute the entire heterogeneity of memory T cell subsets including T SCM cells. [4]

  4. T cell - Wikipedia

    en.wikipedia.org/wiki/T_cell

    Central memory T cells also have intermediate to high expression of CD44. This memory subpopulation is commonly found in the lymph nodes and in the peripheral circulation. (Note- CD44 expression is usually used to distinguish murine naive from memory T cells). Effector memory T cells (T EM cells and T EMRA cells) express CD45RO but lack ...

  5. Naive T cell - Wikipedia

    en.wikipedia.org/wiki/Naive_T_cell

    In immunology, a naive T cell (T h 0 cell) is a T cell that has differentiated in the thymus, and successfully undergone the positive and negative processes of central selection in the thymus. Among these are the naive forms of helper T cells ( CD4 + ) and cytotoxic T cells ( CD8 + ).

  6. Immunological memory - Wikipedia

    en.wikipedia.org/wiki/Immunological_memory

    These cells were named central memory T cells (T CM). They effectively stimulate dendritic cells, and after repeated stimulation they are able to differentiate in CCR7- effector memory T cells. Both populations of these memory cells originate from naive T cells and remain in the body for several years after initial immunization. [14]

  7. Tissue-resident memory T cell - Wikipedia

    en.wikipedia.org/wiki/Tissue-resident_memory_T_cell

    T RM cells develop from circulating effector memory T cell precursors in response to antigen. The main role in formation of T RM cells has CD103 and expression of this integrin is dependent on the cytokine TGF-β. CD8 + effector T cells that lack TGF-β fail to upregulate CD103, and subsequently do not differentiate into T RM cells.

  8. Thymocyte - Wikipedia

    en.wikipedia.org/wiki/Thymocyte

    Thymocytes are classified into a number of distinct maturational stages based on the expression of cell surface markers. The earliest thymocyte stage is the double negative stage (negative for both CD4 and CD8), which more recently has been better described as Lineage-negative, and which can be divided into four substages.

  9. Lymphopoiesis - Wikipedia

    en.wikipedia.org/wiki/Lymphopoiesis

    T-cytotoxic (which kills virally infected cells), T-memory (T cells that remember antigens previously encountered), and; T-suppressor cells (which moderate the immune response of other leukocytes). Also called T-regulatory cells (T reg) When T cells become activated they undergo a further series of developments.