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Dehydration, which is compounded by heat, can result in increasing lithium levels. The dehydration is due to lithium inhibition of the action of antidiuretic hormone, which normally enables the kidney to reabsorb water from urine. This causes an inability to concentrate urine, leading to consequent loss of body water and thirst.
Lithium toxicity can occur due to excessive intake or decreased excretion. [1] Excessive intake may be either a suicide attempt or accidental. [ 1 ] Decreased excretion may occur as a result of dehydration such as from vomiting or diarrhea , a low sodium diet , or from kidney problems . [ 1 ]
Excessive levels of lithium can be harmful to the kidneys, and increase the risk of side effects in general. As a result, kidney function and blood levels of lithium are monitored in patients being treated with lithium. [2] Therapeutic plasma levels of lithium range from 0.5 to 1.5 mEq/L, with levels of 0.8 or higher being desirable in acute ...
Due to lithium's narrow therapeutic index, lithium levels must be monitored regularly for prevention of lithium toxicity. There is also evidence that the anticonvulsants valproate, lamotrigine, carbamazepine, and topiramate are effective in the reduction of symptoms of hypomanic and depressive episodes of bipolar disorder.
Seems intuitive, but lounging in bed too much and sleeping for long periods can make it all worse, says Srijan Sen, M.D., Ph.D., professor of psychiatry and director of the University of Michigan ...
Lithium – Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar).
The saying “knowledge is power” applies well in certain situations — like becoming a leader in your field of expertise or knowing the best places to eat (we all have different skills).
Feelings of depression and anxiety can last nearly a year and a half after a serious bout of Covid-19, according to a study released Monday. The research, published in The Lancet Public Health, is ...
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