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Verrucotoxin (VTX) is a lethal venom produced by the dorsal fins of Synanceia verrucosa. This species of reef stonefish is connected to the family Synanceiidae. The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects. [1]
Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is classified within the family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans.
Synanceia verrucosa are usually brown or grey, and may have areas of yellow, orange, or red. [8] The dorsal fin contains between 12 and 14 spines and 5 and 7 soft rays while the anal fin has 3 spines and 5 or 6 soft rays. [2] The dorsal spines are of equal length with a thicker sheath of skin containing the venom glands at their base.
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Instead of swimming away if disturbed, it erects 13 venomous spines along its back. For defense it can shoot venom from each or all of these spines. Each spine is like a hypodermic needle, delivering the venom from two sacs attached to the spine. The stonefish has control over whether to shoot its venom, and does so when provoked or frightened. [3]