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It is packaged as white, round, biconvex, uncoated tablets, with each tablet containing 30 mg of pseudoephedrine hydrochloride (PSE), 500 mg of paracetamol (acetaminophen) and 2 mg of chlorpheniramine maleate (CPM) as the active ingredients.
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
In seven healthy male subjects, this dose yielded a urine concentration range of 62.8 to 294.4 microgram per milliliter (μg/mL) with mean ± standard deviation 149 ± 72 μg/mL. [124] Thus, normal dosage of 240 mg pseudoephedrine per day can result in urine concentration levels exceeding the limit of 150 μg/mL set by WADA for about half of ...
In 1997, the FDA proposed a regulation on ephedra (the herb from which ephedrine is obtained), which limited an ephedra dose to 8 mg (of active ephedrine) with no more than 24 mg per day. [78] This proposed rule was withdrawn, in part, in 2000 because of "concerns regarding the agency's basis for proposing a certain dietary ingredient level and ...
Naproxen/pseudoephedrine, sold under the brand name Aleve-D among others, is a fixed-dose combination medication used for the treatment of nasal congestion and other symptoms of the common cold. [1] It contains naproxen , as the sodium salt, a nonsteroidal anti-inflammatory drug (NSAID); and pseudoephedrine , as the hydrochloride, a nasal ...
Berberine, a plant compound traditionally used in herbal medicine, is today commonly stocked on the shelves of health food stores and pharmacies as a supplement.. Berberine supplements gained ...
Loratadine's peak effect occurs after 1–2 hours, and its biological half life is on average eight hours (range 3 to 20 hours) with desloratadine's half-life being 27 hours (range 9 to 92 hours), accounting for its long-lasting effect. [34] About 40% is excreted as conjugated metabolites into the urine, and a similar amount is excreted into ...
"Desloratadine and pseudoephedrine combination therapy as a comprehensive treatment for allergic rhinitis and nasal congestion". Expert Opin Drug Metab Toxicol . 5 (6): 683–94.
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