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Modafinil, sold under the brand name Provigil among others, is a central nervous system (CNS) stimulant and eugeroic (wakefulness promoter) medication used primarily to treat narcolepsy, [3] [8] [15] a sleep disorder characterized by excessive daytime sleepiness and sudden sleep attacks. [16]
At steady state, the systemic exposure for armodafinil is 1.8 times the exposure observed after a single dose. The concentration-time profiles of the (R)-(−)-enantiomer following a single dose of 50 mg Nuvigil or 100 mg Provigil (modafinil being a 1:1 mixture of (R)-(−)- and (S)-(−)- enantiomers
Chemical structure of modafinil.. This page lists chemical compounds similar to modafinil, known as modafinil analogues and derivatives.These are structural analogues and derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI).
Armodafinil (Nuvigil, CRL-40982, CEP-10952, (R)-modafinil) – the (R)-enantiomer of modafinil Modafinil (Provigil, Alertec, Modavigil, CRL-40476) – a racemic mixture of armodafinil and esmodafinil Discontinued
Provigil is a combination of R and S isomers of modafinil. Nuvigil uses only the R isomer, with the hope that it will have longer lasting effects in the body. However, Cephalon states that it has no comparative test data on Nuvigil and Provigil, either on efficacy or patient tolerance. Both substances carry a risk of dependency and producing mania.
Weight loss is a personal for everyone, so it’s hard to say that you’ll drop pounds just by having more protein and fiber in your diet. However, eating both may help you feel fuller for longer.
Weight loss of 25%, Moreno and Grunvald noted, would reach results obtained by bariatric surgery. And in Novo Nordisk’s CagriSema trial, 40% of participants did lose at least 25% of their body ...
“Just as much as the GLP-1s are a diabetes drug and a weight loss medicine, they are brain drugs, too,” says Rekha Kumar, MD, an endocrinologist at New York-Presbyterian and Weill Cornell ...