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The fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase was approved for medical use in the United States in June 2020. [5] [10]The FDA's approval was based on the results of a non-inferiority study in participants with HER2-positive early breast cancer, which demonstrated the fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase had comparable efficacy and ...
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Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...
144 674.18 g·mol −1 Cosibelimab , sold under the brand name Unloxcyt , is a monoclonal antibody used for the treatment of cutaneous squamous-cell carcinoma . [ 1 ] It is a programmed death ligand-1 (PD-L1) blocking antibody.
[medical citation needed] Besides, hyaluronidase is a recommended antidote for vinca alkaloid overdose or extravasation. [12] Hyaluronidase can be injected to dissolve hyaluronic acid type dermal fillers and is the best treatment option for those looking at dissolving lip filler or dealing with related complications. [13]
A painting by British artist George Stubbs is expected to sell for up to £2 million ($2.5 million) in London next week, as it comes to auction for the first time in more than 50 years.. The 18th ...
Revumenib, sold under the brand name Revuforj, is an anti-cancer medication used for the treatment of acute leukemias harboring lysine methyltransferase 2A gene (KMT2A) rearrangements. [1] It is designed to disrupt the interaction between menin and KMT2A (also known as MLL), which plays a role in the pathogenesis of these leukemias. [ 2 ]
It has 13 grams of protein for less than 300 calories and contains zero trans fats. To cut back on salt, fat, and sugar, consider skipping the fries and opting for a seltzer water instead of a soda.