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Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
A Janus kinase inhibitor, also known as JAK inhibitor or jakinib, [1] is a type of immune modulating medication, which inhibits the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway in lymphocytes.
Apoquel is a medication prescribed for pets — particularly dogs — to alleviate symptoms associated with allergic dermatitis, such as itching and inflammation. The FDA has not officially ...
acepromazine – sedative, tranquilizer, and antiemetic; afoxolaner - antiparasitic; albendazole - anthelminthic; alphaxolone - hypnotic/sedative; alprazolam – benzodiazepine used as an anxiolytic and tranquilizer
Elanco considers Zenrelia as one of its potential blockbusters. It is the company's first product in the market related to skin disease treatments for dogs, that include Zoetis' oral treatment ...
FDA Approves APOQUEL ® (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation ...
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Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs. [1] It acts against interleukin 31 (IL-31), [2] which is a cytokine involved in causing itchiness (pruritus). [2]