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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
Ondansetron was approved by the U.S. Food and Drug Administration in 1991, and has since become available in several other countries, including the UK, Ireland, Australia, Canada, France and Brazil. As of 2008, ondansetron and granisetron are the only 5-HT 3 antagonists available as a generic drug in the United States. Ondansetron may be given ...
[17] [18] SSRIs and 5-HT 1A receptor agonists often produce nausea as a side effect, whereas 5-HT 3 receptor antagonists like ondansetron are antiemetics and have been found to be effective in treating SSRI-induced nausea. [46] It was thought that the 5-HT 3 receptor antagonism of vortioxetine would reduce the incidence of nausea relative to ...
Take Zofran. If you know you’re prone to motion sickness and vomiting from motion sickness, your doctor might prescribe ondansetron, also known as Zofran. It comes in a pill and liquid form ...
Pharmacotoxicology entails the study of the consequences of toxic exposure to pharmaceutical drugs and agents in the health care field. The field of pharmacotoxicology also involves the treatment and prevention of pharmaceutically induced side effects.
Taking precautions to protect yourself from a quartet of infectious diseases can lessen your odds of starting off 2025 sick. Public health experts are warning of a ‘quad-demic’ this winter.
The phase III trial for approval was published in 2000 as an industry-funded randomized, placebo-controlled trial (PCT). Its authors found 1 mg alosetron, taken orally twice daily for 12 weeks, was associated with a 12% (CI 4.7-19.2) improvement in relief from abdominal pain and discomfort associated with diarrhea-predominant patients. [4]
Dolasetron (trade name Anzemet) is a serotonin 5-HT 3 receptor antagonist used to treat nausea and vomiting following chemotherapy. [1] Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata.
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