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Technetium-99m (99m Tc) is a metastable nuclear isomer of technetium-99 (itself an isotope of technetium), symbolized as 99m Tc, that is used in tens of millions of medical diagnostic procedures annually, making it the most commonly used medical radioisotope in the world.
Technetium-99 (99 Tc) is an isotope of technetium which decays with a half-life of 211,000 years to stable ruthenium-99, emitting beta particles, but no gamma rays. It is the most significant long-lived fission product of uranium fission, producing the largest fraction of the total long-lived radiation emissions of nuclear waste .
Technetium-99m is the hallmark technetium isotope employed in the nuclear medicine industry. Its low-energy isomeric transition, which yields a gamma-ray at ~140.5 keV, is ideal for imaging using Single Photon Emission Computed Tomography (SPECT). Several technetium isotopes, such as 94m Tc, 95 Tc, and 96 Tc, which are produced via (p,n ...
All isotopes of technetium must be handled carefully. The most common isotope, technetium-99, is a weak beta emitter; such radiation is stopped by the walls of laboratory glassware. The primary hazard when working with technetium is inhalation of dust; such radioactive contamination in the lungs can pose a significant cancer risk.
Technetium (99m Tc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow. Single photon emission computed tomography imaging of the heart is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it decays.
The potential to trigger an abrupt release of energy from nuclear isotopes, a prerequisite to their use in such weapons, is disputed. Nonetheless a 12-member Hafnium Isomer Production Panel (HIPP) was created in 2003 to assess means of mass-producing the isotope. [22] Technetium isomers 99m 43 Tc (with a half-life of 6.01 hours) and 95m 43 Tc
In particular, 99 Tc (half-life 211,000 years) is used in corrosion research, because it is the decay product of the easily obtained commercial 99m Tc isotope. [3] Solutions of technetate(VII) react with the surface of iron to form technetium dioxide, in this way it is able to act as an anodic corrosion inhibitor .
99m Tc is a very versatile radioisotope, and is the most commonly used radioisotope tracer in medicine. It is easy to produce in a technetium-99m generator, by decay of 99 Mo. 99 Mo → 99m Tc + e − + ν e. The molybdenum isotope has a half-life of approximately 66 hours (2.75 days), so the generator has a useful life of about two weeks.