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Bimatoprost, sold under the brand name Lumigan among others, is a medication used to treat high pressure inside the eye including glaucoma. [5] Specifically it is used for open angle glaucoma when other agents are not sufficient. [5] [6] It may also be used to increase the size of the eyelashes.
Bimatoprost/timolol, sold under the brand name Ganfort, is a medication for the treatment of certain conditions involving high pressure in the eyes, specifically open angle glaucoma and ocular hypertension. [1] [3] It is available as eye drops. [1] [3] It was approved for medical use in the European Union in May 2006. [3]
Bimatoprost: Lumigan: Increased USO (uveoscleral outflow ) Once daily: blurred vision, eyelid redness, eye discomfort, permanently darken iris, darken/thicken eyelashes Travoprost: Travatan: Increased USO (uveoscleral outflow ) Once daily: blurred vision, eyelid redness, eye discomfort, permanently darken iris, darken/thicken eyelashes Beta ...
This work led to the development of prodrugs of PGF2α, including latanoprost, an isopropyl analogue of PGF2α, approved by the FDA in 1996, bimatoprost and travoprost, both approved in 2001, and tafluprost, approved in 2012. [1]
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Nicox's lead program in clinical development is NCX 470, a novel, second-generation nitric oxide-donating bimatoprost analog, for lowering intraocular pressure (IOP) in patients with glaucoma. [6] NCX 470 is designed to release both bimatoprost, which is marketed under the brand name LUMIGAN, and nitric oxide following instillation into the eye ...
The FP receptor agonist, bimatoprost, in the form of an 0.03% ophthalmic solution termed Latisse, is approved by the US Food and Drug Administration to treat hypotrichosis of the eyelashes, in particular to darken and lengthen eyelashes for cosmetic purposes. [59] Also, bimatoprost may be used to treat small or underdeveloped eyelashes. [60] [61]
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